Researchers from the Whitehead Institute for Biomedical Research modified red blood cells with disease-specific antigens to prevent and alleviate multiple sclerosis and Type I diabetes in early stage mouse models. The team’s work was published this week in PNAS.
Conventional therapies for autoimmune diseases include immunosuppressants, but these drugs can desensitize the immune system’s response to pathogens. Instead, the team of researchers employed red blood cells tagged with antibodies to train the immune system to ignore antigens that cause the body to attack itself.
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